Im Rahmen der vorliegenden Arbeit wurde der Basidiomycet Cerrena unicolor (Cun) als Sesquiterpenproduzent untersucht. Im Genom des Pilzes konnten mit Hilfe von Sequenzvergleichen 14 Sesquiterpensynthasen (STS) identifiziert ...

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The filamentous fungus Trichoderma reesei is a well-known source of cellulase enzymes in many industrial applications. Nevertheless, its use as a host for heterologous expression is limited. In this study, many promoters ...

Die Brotherstellung ist eine der ältesten bekannten Biotechnologien. Die kontinuierliche Verbesserung dieses Prozesses vollzog sich parallel der Entwicklung zu einer modernen zivilisierten Gesellschaft. Um schwankende ...

Trichoderma reesei (Hypocrea jecorina) was developed as a microbial cell factory for the heterologous expression of fungal secondary metabolites. This was achieved by inactivation of sorbicillinoid biosynthesis and ...

Oxidative rearrangements are key reactions during the biosyntheses of many secondary metabolites in fungi. This review highlights the most important examples of these reactions and aims to draw together key mechanistic ...

The trili biosynthetic gene cluster (BGC) from the well-studied organism Trichoderma reesei was studied by heterologous expression in the fungal host Aspergillus oryzae. Coexpression of triliA and triliB produces two new ...